The conference was inspiring 和 I came back enthusiastic to try a variety of new approaches, both on myself 和 my 患者s. 粪便移植 和 蠕虫疗法 在我的清单上排名很高，但是粪便和蠕虫仍然很难获得并且管理起来很复杂。相比之下，另一种方式 低剂量纳曲酮 （LDN）是一种常规药物，容易获得，安全，便宜，并且根据讲师的讲授，具有广泛的适用性和功效。
I have been aware of the existence of 低剂量纳曲酮 for some time, but never considered prescribing it to my 患者s or taking it myself, until I heard the lecture at the conference. Two physicians, 伦纳德·怀恩斯托克（马里兰州） 和 吉尔·科特尔（Jill Cottel）, who have extensive experience using it with large numbers of 患者s, reported that they often had excellent results in terms of achieving improvement 和 even remission in a wide variety of conditions. There are studies reporting its efficacy not only in classic auto immune illnesses such Ulcerative Colitis, Rheumatoid Arthritis, Multiple Sclerosis 和 Psoriasis, but also in diverse conditions such as Cancer, 纤维肌痛, 慢性疲劳, 组胺不耐受 和 肥大细胞活化障碍, Autism, Chronic Pain 和 Complex Regional Pain Syndrome, AIDS, 创伤后应激障碍 和 Depression.
纳曲酮, an opiate antagonist, was developed in 1963. Originally 纳曲酮 50 mg three times a day was prescribed to treat opioid addiction 和 alcoholism. Due to receptor blockade, 患者s taking 纳曲酮 would not get high from opioids or alcohol. Unfortunately it was very poorly tolerated 通过 患者s. It resulted in dysphoria, as it not only blocked the effects of the intoxicants, but also blocked the naturally occurring 内啡肽 在身体里。患者不喜欢这种感觉，因此拒绝服用。内啡肽是自然产生的物质，可以产生健康感，例如长跑运动员的欣快感。它们在调节免疫反应以及减轻疼痛和炎症中也起重要作用。
低剂量纳曲酮 is contraindicated in 患者s who are taking pain medications 和 immune suppressive therapies. It must be obtained from a compounding pharmacy 和 generally costs less than one dollar a day. I obtained a 90 day supply from 约翰逊’复合与健康 in Waltham, MA for $49.95. Low Dose 纳曲酮 is available only with a prescription. A couple of days ago, I started myself 和 a number of my 患者s on 1.5 mg. I will evaluate in two weeks if the dosage should be increased. It is preferable to take the smallest possible effective dose.
有趣的是 医学博士尼尔·内森（Neil Nathan） an expert who I often consult when I have 患者s in my practice with mold toxicity, wrote in a private communication that he never has seen 低剂量纳曲酮 work in any auto immune condition. He wrote that it sometimes helps with energy 和 cognition. Amy Myers, MD the well known integrative physician, also wrote in a 发布 that she has not witnessed dramatic results with her 患者s. It’s hard to know how to understand these discrepancies. The presenters at the conference reported impressive results in many cases, though not all. I am now taking the medication myself 和 prescribing it to many of my 患者s. The risk is low 和 the potential benefit high.
After my first dose, I slept restlessly 和 had a moderate headache the next day. The next two nights I slept better 和 had no headache, 和 had an elevated mood. I am interested in its capacity to reduce gut permeability 和 the permeability of the blood brain barrier. Most 患者s who come to see me have psychiatric symptoms which are caused 通过 a leaky gut, a leaky brain 和 inflammation.
这证明了常规药物在功能医学会议上被采用，以及像这样的组织多年以来的潜在高收益和低风险。 韦斯顿A价格基金会 一直是其潜在利益的强烈支持者。
My thinking is as follows: our current environment is so toxic 和 stressful, that we need to make use of all possible measures to strengthen our immunity, in order to maintain our health. I am really excited about the potential of 低剂量纳曲酮, 和 eager to see if it helps me 和 my 患者s. I will report back with my findings.
Here is a fascinating interview 通过 Joseph Mercola, MD of Thomas 科万, MD about 低剂量纳曲酮.